Man applying antiperspirant
Man applying antiperspirant
Man applying antiperspirant

Hyperhidrosis? Try the Best Antiperspirant for Sweat Control

Looking for the best antiperspirant? Here’s what to consider, plus some of the top products.

Feb 6, 2025

Written by

Angela Myers

There are many unavoidable inconveniences in life: Traffic jams, your favorite show being cancelled, and a rainy day when you forgot your umbrella—to name a few. But ineffective sweat protection shouldn’t make the list. For many people with hyperhidrosis (excessive sweating), it unfortunately makes that list too often. 

To stop the spread of ineffective sweat protection, we researched the most popular antiperspirants. Here are the ones that live up to the hype, either as a standalone act or in combination with other products

How Antiperspirants Work To Stop Sweat

Antiperspirants are effective in 85% of mild hyperhidrosis cases. Their power stems from their active ingredients: Aluminum salts. These salts form a gel-like plug on the skin’s surface, stopping excessive sweating. To be classified as an antiperspirant by the FDA, a product must have an aluminum compound, though there are different types. 

Some, like aluminum chloride hexahydrate, are used in prescription products (aka the ones prescribed for mild hyperhidrosis). Others, like aluminum chlorohydrate and aluminum zirconium trichlorohydrex, are used in over-the-counter clinical strength antiperspirants (aka the ones for normal sweating). 

Types of Antiperspirants

While we traditionally think of an antiperspirant as a roll-on stick for the underarms (similar to a deodorant), it also comes in creams, sprays, gels, and wipes, making it a great option for excessive sweating on any body part.

And if you heard the word deodorant and thought, “Why don’t I just use that?” We get it. It’s easy to confuse the two, but deodorants mask odors while antiperspirants block the sweat ducts and stop sweat.

Best OTC Antiperspirants for Hyperhidrosis

Now that we know what an antiperspirant is, what are the best over-the-counter antiperspirants? The exact answer depends on what you’re looking for. Below, we outlined the strongest OTC antiperspirant, as well as the ones suitable to sensitive skin or an on-the-go lifestyle.

Best Clinical-Strength Antiperspirant 

Product: Carpe

Price: Ranges based on product

Active Ingredients: Varies depending on the exact product

Why we picked it: If you enjoy physical activity or are constantly on-the-go, Carpe may be a good choice. This brand has a number of products, meaning there’s a solution for sweating in any part of the body, and multiple antiperspirant types to choose from (powder, lotion, stick, serums, and wipes). Plus, these products have a higher concentration of aluminum salts than other OTC options. 

Pros: 

  • Higher concentration of aluminum salts

  • Wide variety of products

  • Products focused on hands, underarms, face, and feet

Cons:

  • Not as effective for moderate to severe hyperhidrosis 

  • Scents can be overpowering 

Best Antiperspirant for Sensitive Skin

Product: Dove Invisible Antiperspirant 

Price: $3.99-$25, depending on size and shopping location

Active Ingredients: Aluminum Chlorohydrate (19.6%)

Why we picked it: This product from Dove is a great option for someone with mild hyperhidrosis or sweating and sensitive skin. Because it’s unscented, includes moisturizer, and is made with a 0% (ethanol) alcohol formula, it doesn’t irritate the skin. 

Pros: 

  • Made with sensitive skin in mind

  • High concentration of aluminum salts

  • Unscented

Cons: 

  • Designed for underarms only

  • Only comes in stick form

Best Sweat Wipes for On-the-Go Protection

Product: Duradry Sweat Wipes

Price: $40-80, depending on how many you buy

Active Ingredients: Aluminum Chlorohydrate

Why we picked it: The Duradry sweat wipes provide great all-around protection and are easy to take on the go. Not only do these products provide fragrance-free sweat protection in easy-to-use wipes, they’re also easy to order with Duradry’s auto-deliver option.

Pros: 

  • High effectiveness rate 

  • Can work for most body parts

  • 97% of the ingredients are natural

Cons:

  • Doesn’t list the concentration of the active ingredient 

  • Pricier than other options

Best Antiperspirants for Specific Body Areas

Focal hyperhidrosis, excessive sweating in concentrated body parts, accounts for 93% of primary hyperhidrosis cases. To combat focal hyperhidrosis, many companies have designed best-in-class solutions for sweat-prone areas. Ahead are the best OTC options for underarms, face, hands, feet, and groin, though prescription options exist for specific body parts too. 

Best Antiperspirant for Underarms

Product: Carpe Underarm Max Strength Lotion

Price: $19.95 each

Active Ingredients: Aluminum Sesquichlorohydrate (15%)

Why we picked it: When it comes to underarm sweating, Carpe provides one of the best solutions. This quick-drying nighttime antiperspirant works efficiently and comes in a variety of scent options. For those with sensitive skin, Carpe has a fragrance-free option. 

Pros: 

  • Various scent options, including fragrance free

  • Designed specifically for underarms

  • Dermatologist tested

Cons:

  • Best used at night

  • Takes about four weeks to work

Best Antiperspirant for Hands & Palms

Product: SweatBlock Hand Lotion

Price: $16.99 per lotion

Active Ingredients: Aluminum Sesquichlorohydrate (17.5%)

Why we picked it: When it comes to hand antiperspirants, SweatBlock stands out because of its clean, natural ingredient list and long-lasting formula. It also comes with a 100-day money-back guarantee, making it a low-risk option financially. 

Pros: 

  • Designed specifically for hands

  • Offers a no-slip feature that helps you better grip with sweaty palms

  • Long-lasting 

Cons: 

  • May not help with moderate or severe cases of hyperhidrosis

  • Must spend over $30 to get free shipping

Best Antiperspirant for Feet

Product: Australian Bodycare Foot Spray

Price: $16.99

Active Ingredients: Aluminum Chlorohydrate

Why we picked it: When it comes to feet antiperspirants, the International Hyperhidrosis Society recommends aerosol products you can spray onto the soles of the feet. Australian Bodycare meets that recommendation.

Pros: 

  • Spray can be used on feet or shoes

  • Vegan

  • Includes tea tree oil to combat foot odor

Cons: 

  • Doesn’t specify concentration of aluminum salts 

  • May not work for moderate or severe hyperhidrosis 

Best Antiperspirant for Face & Forehead

Product: SweatBlock Face Antiperspirant Wipes

Price: $17.99 each

Active Ingredients: Aluminum Chlorohydrate

Why we picked it: Antiperspirants are not recommended as often for face sweating, but this  particular antiperspirant is especially useful for the face and scalp. Not only do these wipes control face sweating, they also act as makeup protection and may reduce oil, which could lead to better overall skin health.

Pros: 

  • Specifically for the face and scalp

  • Clinically tested

  • Designed to control shine and oil, as well as sweat

Cons: 

  • Doesn’t list active ingredient concentration

  • Each pack only includes 15 wipes, which means you may have to buy this product more often than others on the market

Best Antiperspirant for Groin & Private Areas

Product: Carpe Women’s Groin Powder and Men’s Groin Powder

Price: $19.95 each

Active Ingredients: Aluminum Starch Octenylsuccinate 

Why we picked it: If you’re looking to stop groin sweat, consider this antiperspirant powder from Carpe. Both products were designed without talc in order to avoid friction and have a minimal ingredient list to avoid skin irritation. 

Pros:

  • Products designed for men and women

  • Vegan

  • Dermatologist tested

Cons:

Best Prescription Antiperspirants for Hyperhidrosis

Most of the products we’ve discussed are over the counter, meaning you can get them without a prescription. For more severe cases, you may need to see a healthcare provider who can write you a prescription for a strong antiperspirant. 

In these cases, the best anti-sweat products are whatever the healthcare provider recommends, keeping in mind that treatment should be adjusted if any products cause uncomfortable side effects or don’t prove effective.

When Antiperspirants Aren’t Enough 

While antiperspirants are a great standalone option, they sometimes aren’t enough as a solo act. If you have moderate or severe hyperhidrosis, another solution may be needed—either in place of or accompanying antiperspirants. 

Accompanying or Alternative Hyperhidrosis Treatments

For heavy sweat, consider the following treatment options: 

  • Anticholinergics: Oral medications that can block sweat gland activity. 

  • Iontophoresis: A machine that slows sweating via an electrical current delivered through water.  

  • Botox: While commonly known for reducing wrinkles, this injection can reduce sweat gland activity too.  

  • MiraDry: A sweat reduction treatment specifically for the armpits. 

  • Surgery: For more advanced hyperhidrosis cases, surgery may be required. Endoscopic thoracic sympathectomy (ETS) and sweat gland removal are the most common procedures.

Before starting any treatment, consult a healthcare provider to make sure it works well with any other medications you’re taking or antiperspirants you’re using. 

Alternatives for Mild Sweat

If you’ve ever asked if antiperspirants are safe, it’s a good question. They have minimal side effects, though some people are more at-risk of developing them. If you have contact dermatitis or sensitive skin, there’s a chance an over–the-counter antiperspirant may irritate the skin or cause a rash. In these cases, it may be best to opt for more natural deodorants or other mild hyperhidrosis treatment options, such as supplements or sage.

Others find that lifestyle adjustments provide enough sweat and odor protection. Common lifestyle changes (that can be made with or without antiperspirants) include:

  • Wearing loose-fitting clothes

  • Avoiding spicy foods

  • Opting for smaller amounts of caffeine and alcohol 

  • Managing stress levels

If you’re avoiding antiperspirants because of the rumors that they cause breast cancer and other serious side effects, we’re here to bust that myth once and for all: Antiperspirants have not been linked to any type of cancer.

How To Apply Antiperspirant for Maximum Effectiveness

Skin irritation or a rash are potential side effects of antiperspirants, but there are steps you can take to avoid them—and to make prescription or over-the-counter antiperspirants as effective as possible. 

Best practices to follow include:

  • Use as intended: Read the instructions on your specific product and use as intended.

  • Apply the right way: Gently massage the antiperspirant into the skin and apply only when the skin is completely dry.

  • Reapply when needed: Use antiperspirants at night in mild to moderate cases. Severe cases might require twice daily use (in the morning and at night). 

  • Keep on for 6-8 hours: When using at night, keep antiperspirants on for six to eight hours before washing off. 

  • Combine treatments: Many people with hyperhidrosis consider it useful to combine an antiperspirant with other treatment options. Only do so with the guidance of a healthcare provider.

Common Mistakes That Reduce Effectiveness

Everybody makes mistakes, but we can all avoid the three most common antiperspirant errors. The first is buying a deodorant-antiperspirant combo product with a weak concentration of aluminum salts. These combo products are enticing, since they promise to stop bad smells and sweat production all at once, but they have to have a high enough concentration of these salts to work. And what is a high enough concentration? 6.5% aluminum salts is the minimum. 

Another common error is to use a product with fragrances or other ingredients that cause side effects. Antiperspirants that smell like lavender, vanilla, or insert-your-favorite-scent-here are great in theory, but not so great if your skin is easily irritated. Similarly, if an antiperspirant causes white marks on clothes or leaves a sticky residue, you may want to look for another product. 

The third common mistake is to expect an antiperspirant to work ASAP. We live in a world where our coffee orders are ready in less than five minutes and we DoorDash food right to our doorstep, but antiperspirants take longer to work. Most experience the first impacts within six to eight hours. Consistent use over several weeks is required to notice a lasting difference. 

And the Best Antiperspirant Is…

Whichever antiperspirant is best for you! While this might not be a cut-and-dry answer you’d hope for, hyperhidrosis treatment isn’t one-size-fits-all. It’s about finding the right treatment line-up for your sweat severity and symptoms. 

Working with a qualified healthcare provider who has experience treating hyperhidrosis is the best way to get that tailor-made treatment plan. At SweatRx, we can connect you with a board-certified dermatologist and ship prescribed treatments right to your door.